Therapeutic Drug Monitoring

One of the goals of PacTox is to assist providers to maximize the benefits of drug therapy while minimizing toxicity for each patient. The absorption and elimination rates for a drug can be significantly different between patients. This is true even though prescribed medications are within the standard “therapeutic range”.

Therapeutic drug monitoring requires coordination between the provider and the laboratory. Clinical correlation must be made with laboratory results in order to fully and accurately interpret the significance of the results. For example, the laboratory must know the drugs and dosage the patient is taking, prescribed or drugs of abuse if known or when use is suspected. This information aids the laboratory in employing additional steps in providing full information for the submitted specimen. Some drugs have toxicities that occur at concentrations quite close to the therapeutic concentrations needed to provide the intended benefit. The treatment plan for these patients requires close and continued monitoring.

The range of drugs is broad and detailed consideration is best considered for a drug and/or for a class of drugs, e.g., anticonvulsants, workplace drugs, opiates, lead, etc. Our website includes this information.

Please select a test for more information.

Name Method Code
Amiodarone (Cordarone)90070HPLCmore info
Chloramphenicol (Chloromycetin), Serum90000HPLCmore info
Chloromycetin (Chloramphenicol), Serum90000HPLCmore info
Codeine -Serum90185GC-NPDmore info
Cordarone (Amiodarone)90070HPLCmore info
Depakene (Valproic Acid) Total90047FPIAmore info
Depakote (Divalproex) (Measured as Valproic Acid)90047FPIAmore info
Fluphenazine (Prolixin)90082HPLCmore info
Haloperidol (Haldol)90084HPLCmore info
Prolixin (Fluphenazine)90082HPLCmore info
Stelazine (Trifluoperazine)90071HPLCmore info
Trifluoperazine (Stelazine)90071HPLCmore info
Valium (Diazepam) & Nordiazepam, Blood90092HPLCmore info
Valproic Acid (Depakene) - Total90047FPIAmore info
Acetaminophen (Tylenol)90145EIAmore info
Acetylsalicylic Acid (as Salicylates)90041Enzymatic more info
Advil (Ibuprofen)90001GC-FIDmore info
a-Hydroxy-Alprazolam, Urine90143GC/MSmore info
Alpha-hydroxy-alprazolam, Urine90143GC/MSmore info
Alprazolam & Alpha-hydroxy-alprazolam,Urine90186GC/MSmore info
Alprazolam (Xanax)90086GC-ECDmore info
Ambien (Zolpidem)90168HPLCmore info
Amitriptyline (Elavil) & Nortriptyline90002HPLCmore info
Amobarbital (Amytal)90043GC-FIDmore info
Amorbarbital, Urine90139GC-FIDmore info
Amytal (Amobarbital)90043GC-FIDmore info
Anafranil (Clomipramine) & Desmethylclomipramine90034HPLCmore info
Antidepressant Screen(Contact Lab)90172HPLCmore info
Aspirin (as Salicylates)90041FPIAmore info
Ativan (Lorazepam), Serum90083GC-ECDmore info
Aventyl (Nortriptyline)90003HPLCmore info
Aventyl (Nortriptyline) - Urine90006HPLCmore info
Benadryl (Diphenhydramine)90039GC-NPDmore info
Benzodiazepine Screen,Blood,Serum,Urine90124GC-ECD, HPLC, GCMSmore info
Benzodiazepines Quant/Confirmation Urine93017GC/MSmore info
Benzodiazepine Confirmation, Urine,Serum,Blood90176GC-ECDmore info
Benzoylecgonine (BE) CocaineQuant/Conf Urine93012GC/MSmore info
Bupropion (Wellbutrin) and Hydroxybupropion90099HPLCmore info
Butabarbital (Butisol)90108GC-FIDmore info
Butalbital, Urine90138GC/MSmore info
Butalbital (Fiorinal) - Serum90044GC-FIDmore info
Butisol (Butabarbital)90108GC-FIDmore info
Capsule Analysis90746GC-FID, GC/MSmore info
Carisoprodol (Soma) & Meprobamate90064GC-FIDmore info
Celexa (Citalopram & Desmethylcitalopram)90188HPLCmore info
Chlordiazepoxide (Librium) & Metabolite90087HPLCmore info
Chlorpromazine (Thorazine)90085HPLCmore info
Citalopram & Desmethylcitalopram (Celexa)90188HPLCmore info
Clomipramine (Anaframil) & Desmethylclomipramine90034HPLCmore info
Clonazepam (Klonopin)90114GC-ECDmore info
Clorazepate (Tranxene), As Nordiazepam90077HPLCmore info
Clozapine (Clozaril) and Desmethylclozapine90101HPLCmore info
Clozaril (Clozapine) and Desmethylclozapine90101HPLCmore info
Codeine & Morphine, Blood90185GC/MSmore info
Codeine & Morphine Quant/Conf Urine (Opiates Confirmat93013GC/MSmore info
Codeine, Urine90144GC/MSmore info
Cyclobenzaprine (Flexeril)90121HPLCmore info
Dalmane (Flurazepam) & Desalkylflurazepam90113GC-ECDmore info
Darvocet Profile90753GC-NPD, FPIAmore info
Darvon (Propoxyphene) & Norpropoxyphene - Serum90036GC-NPDmore info
Demerol (Meperidine) & Normeperidine - Urine90095GC/MSmore info
Demerol (Meperidine)& Normeperidine - Serum90094GC-NPDmore info
Desyrel (Trazodone)90073HPLCmore info
Diazepam & Nordiazepam, Urine90192GC/MSmore info
Diazepam (Valium) Nordiazepam, Blood90092GC(EC)more info
Diphenhydramine (Benadryl)90039GC-NPDmore info
Divalproex (Depakote) (as Valproic Acid)90047FPIAmore info
Dolophine (Methadone) - Blood90198GC-NPDmore info
Doriden (Glutethimide)90210GC-FIDmore info
Doxepin (Sinequan) and Desmethyldoxepin90028HPLCmore info
Effexor (Venlafaxine)90226HPLCmore info
Elavil (Amitriptyline) & Nortriptyline90002HPLCmore info
Ephedrine93112GC/MSmore info
Equanil (Meprobamate)90066GC-FIDmore info
Fentanyl (Innovar)90161GC-NPDmore info
Fioricet Profile90755GC-FID, FPIA, HPLCmore info
Fiorinal (Butalbital)90044GC-FIDmore info
Flexeril (Cyclobenzaprine)90121HPLCmore info
Flunitrazepam (Rohypnol) Urine, qualitative90062GC/MSmore info
Fluoxetine (Prozac) & Norfluoxetine90061HPLCmore info
Flurazepam (Dalmane) & Desalkylflurazepam90113GC-ECDmore info
Fluvoxamine (Luvox)90231HPLCmore info
Gabapentin (Neurontin)90023GC/MSmore info
Gamma-Hydroxybutyric Acid (GHB)90051GC/MSmore info
GHB (Gamma-Hydroxybutyric Acid)90051GC/MSmore info
Glutethimide (Doriden)90210GC-FIDmore info
Halcion (Triazolam)90072GC-ECDmore info
Hydrocodone (Hycodan),Urine93024GC/MSmore info
Hydromorphone (Dilaudid) Urine93023GC/MSmore info
Ibuprofen (Advil, Motrin, Nuprin, Rufen)90001GC-FIDmore info
Inderal (Propranolol)90104HPLCmore info
Innovar (Fentanyl) -serum90161GC-NPDmore info
Innovar (Fentanyl) -urine91161GC-NPDmore info
Keppra (Levetiracetam)90009GC-FIDmore info
Ketamine (serum)91166GC/MSmore info
Ketamine (urine)90166GC/MSmore info
Klonopin (Clonazepam)90114GC-ECDmore info
Levetiracetam (Keppra)90009GC-FIDmore info
Librium (Chlordiazepoxide) & Metabolite90087HPLCmore info
Lidocaine (Xylocaine) -total90022FPIAmore info
Lopressor (Metoprolol)90162HPLCmore info
Lorazepam (Ativan), Serum90083GC-ECDmore info
Lorazepam (Ativan), Urine90183GC/MSmore info
Luvox (Fluvoxamine)90231HPLCmore info
Mellaril (Thioridazine) & Mesoridazine90096HPLCmore info
Meperidine (Demerol) & Metabolite - Urine90095GC/MSmore info
Meperidine (Demerol) & Metabolite - Blood90094GC-NPDmore info
Meperidine Dosage Form90747GC, GC/MSmore info
Meprobamate (Miltown, Equanil)90066GC-FIDmore info
Mesoridazine (Serentil)90075HPLCmore info
Methadone & Metabolite Quant/Confirmation Urine93022GC/MSmore info
Methadone (Dolophine) - Blood90198GC-NPD, GC/MSmore info
Metoprolol, (Lopressor)90162HPLCmore info
Mexiletine (Mexitil)90128HPLCmore info
Mexitil (Mexiletine)90128HPLCmore info
Midazolam (Versed)90081GC-ECDmore info
Miltown (Meprobamate)90066GC-FIDmore info
Morphine - Urine, Quantitation91145GC/MSmore info
Morphine -Blood, Quantitation90207GC/MSmore info
Morphine Dosage Form90209GC/MSmore info
Morphine -Free and Total90208GC/MSmore info
Motrin (Ibuprofen)90001GC-FIDmore info
Nembutal (Pentobarbital)90045GC-FIDmore info
Neurontin (Gabapentin)90023GC/MSmore info
Nordiazepam, Urine90116GC, GC/MSmore info
Nortriptyline (Aventyl) -Serum90003HPLCmore info
Nortriptyline (Aventyl) -Urine90006HPLCmore info
Nuprin (Ibuprofen)90001GC-FIDmore info
Opiates Confirmation Urine93013GC/MSmore info
Oxazepam (Serax) - Serum90105HPLCmore info
Oxazepam (Serax) - Urine90115GC/MSmore info
Oxycodone (Percodan),Urine93025GC/MSmore info
Oxymorphone (Numorphan),Urine93026GC/MSmore info
Pamelor (Nortriptyline)90003HPLCmore info
Paroxetine (Paxil)90751HPLCmore info
Paxil (Paroxetine)90751HPLCmore info
PEMA (Phenylethylmalonamide)90127GC-FIDmore info
Pentabarbital, Urine90135GC/MSmore info
Pentobarbital (Nembutal)90045GC-FIDmore info
Phenergan (Promethazine)90037GC-NPDmore info
Phenobarbital -total90194FPIAmore info
Phenobarbital, Urine90136GC/MSmore info
Phenothiazine, Screen - Serum, Plasma, Urine90125HPLCmore info
Phentermine93114GC/MSmore info
Phenylethylmalonamide (PEMA)90127GC-FIDmore info
Phenylpropanolamine93111GC/MSmore info
Promethazine (Phenergan)90037GC-NPDmore info
Propoxyphene & Norpropoxyphene Urine93018GC/MSmore info
Propoxyphene (Darvon) & Norpropoxyphene -Serum90036GC-NPDmore info
Propranolol (Inderal)90104HPLCmore info
Protriptyline (Vivactyl)90024HPLCmore info
Prozac (Fluoxetine) & Norfluoxetine90061HPLCmore info
Pseudoephedrine93113GC/MSmore info
Quetiapine (Seroquel)90069HPLCmore info
Restoril (Temazepam)90078HPLCmore info
Rohypnol (Flunitrazepam) Urine, qualitative90062GC/MSmore info
Salicylates90041Enzymaticmore info
Secobarbital (Seconal) - Blood90046GC-FIDmore info
Secobarbital, Urine90137GC/MSmore info
Serax (Oxazepam) - Serum90105HPLCmore info
Serax (Oxazepam) - Urine90115GC/MSmore info
Serentil (Mesoridazine)90075HPLCmore info
Seroquel (Quetiapine)90069HPLCmore info
Sertraline (Zoloft) & Desmethylsertraline90749HPLCmore info
Sinequan (Doxepin) & Desmethyldoxepin90028HPLCmore info
Soma (Carisoprodol) & Meprobamate90064GC-FIDmore info
Syringe Analysis (Quantitative)90227GC-FID, GC/MSmore info
Syringe analysis (Unknown)90227GC-FID, GC/MSmore info
Tablet Analysis -Unknown90746GC-FID, GC/MSmore info
Temazepam (Restoril)90078HPLCmore info
Temazepam, Urine90178GC/MSmore info
Thioridazine (Mellaril) & Mesoridazine90096HPLCmore info
Thorazine (Chlorpromazine)90085HPLCmore info
Topamax (Topiramate)90170GC-FIDmore info
Topiramate (Topamax)90170GC-FIDmore info
Tranxene (Clorazepate) As Nordiazepam90077HPLCmore info
Trazodone (Desyrel)90073HPLCmore info
Triazolam (Halcion)90072GC-ECDmore info
Tricyclic Screen (Antidepressant Screen)90172HPLC, GC-NPDmore info
Tylenol (Acetaminophen)90145FPIAmore info
Venlafaxine (Effexor)90226HPLCmore info
Verapamil and Norverapamil90167HPLCmore info
Versed (Midazolam)90081GC-ECDmore info
Vivactyl (Protriptyline)90024HPLCmore info
Wellbutrin (Bupropion) and Hydroxybupropion90099HPLCmore info
Xanax (Alprazolam)90086GC-ECDmore info
Xylocaine (Lidocaine) -total90022FPIAmore info
Zoloft (Sertraline) & Desmethylsertraline90749HPLCmore info
Zolpidem (Ambien)90168HPLCmore info
EtG-EtS91158Screen EIA - Confirm LCMS/MSmore info
Amphetamines, Blood90335GC/MSmore info